In general it’s best to use your body on a variety of surfaces and terrain, so as not to overuse certain parts. But if you have strong, conditioned feet then standing for long periods of time in barefoot shoes shouldn’t be an issue. However, if you are new to barefoot shoes and concerned about being uncomfortable, consider an option with a thicker sole to begin with or adding a barefoot insole (that has no heel rise!) to your shoes. Here are several barefoot shoe options with a sole thickness of at least 10mm.
You can also improve the natural padding on the bottoms of your feet by exposing them to different textures. Here are some tips for adding foot texture to your life.
Muscle Use While Walking on Uneven Terrain – research study